Thrombotic Risks: A Clarification

Thrombotic risks: a clarification.

To the Editor: Rogier M. Bertina has written a clear, timely, and authoritative review of factor V Leiden and other coagulation factor mutations affecting thrombotic risk (1). I was confused by the fact that the sum of genetic defects in inherited thrombophilia plus the cases with unknown cause add up to 109.7% (Table 1 of reference 1). This could occur due to multiple defects in individual pat...

Coordination: A Clarification

Ever since Hayek’s 1937 classic, “Economics and Knowledge,” Austrians and other sympathetic writers have rightly emphasized study of the coordination properties of an economic system. To this end, they have claimed a distinction between the Hayekian focus on coordination and the neoclassical focus on equilibrium and efficiency. Although genuine and important, this distinction has yet to be sati...

Clarification

Note of clarification: Potential risks to offspring of intrauterine exposure to maternal age-related obstetric complications.

Several hypotheses have been proposed to explain the negative effects of delayed motherhood on an offspring's morbidity later in life. However, these hypotheses are not supported by clinical and epidemiological evidence. Because advanced maternal age is associated with increased risk of obstetric complications, the aim of the present study was to ascertain whether the negative effects on offspr...

Mises’ Calculation Argument: a Clarification

IN THIS ARTICLE I WILL DISCUSS MISES’ FAMOUS argument concerning economic calculation under socialism. I will point out that there are in fact two components of this argument. The first part deals with the fact that in capitalist economies, factors of production are allocated based on profit-andloss calculations in terms of (money) prices. Inasmuch as such calculations cannot be performed under...